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SPbPU Analytical Center for Nano- and Biotechnologies Shared Research Center

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Production of pure target protein samples for scientific research and biotechnological development.

Organization type: Laboratory

General information
Contacts

General information

List and cost of services provided
The main list of standard works and services is performed in accordance with the list of developed methodologies
  1. Cloning, isolation, and purification of target protein complexes
  2. Creation of recombinant bacteriophages carrying proteins and peptides, including those toxic to the cell
  3. Characterization of CRISPR-Cas systems and Cas nucleases for further application in genome editing
  4. Development of diagnostic systems for various infectious diseases
  5. Determination of protein-DNA binding sites using NMR and high-resolution mass spectrometry
  6. Visualization of intracellular structures by localization microscopy with 10-40 nm resolution
  7. Visualization of intracellular structures by expansion microscopy
  8. Analysis of protein-protein interactions using two-hybrid systems
  9. Measurement of interaction forces of biological structures at the single-molecule level in the 0.1-200 pN range
  10. Single-molecule study of the dynamics of DNA-protein complex formation and dissociation using the optical trap method
  11. Studies of the mechanical properties of cell membranes using the optical trap method
  12. Single-molecule level study of the influence of antibacterial agents on the transcription process using an acoustic trap
  13. Single-cell level study of stochastic processes associated with target gene expression using fluorescence microscopy
  14. Single-cell level study of the nature and dynamics of phage infection in bacterial cells using microscopy and fluorescence
  15. Chromato-mass spectrometric determination of various pharmaceuticals in human fluids (blood plasma, tears, urine)
  16. Methodology for determining genetic polymorphisms based on CRISPR-Cas
  17. Bacterial genome editing using CRISPR-Cas
  18. Suppression of bacterial gene expression based on CRISPR-Cas (CRISPR interference)
  19. Measurement of ATPase activity of enzymes by spectrophotometric method

Contacts

Website: https://ckp-nanobio.spbstu.ru/price/
Address: 195 251, Russia, Saint Petersburg, Politekhnicheskaya st., 29, Hydrocorpus-2, room 108
Phone: +7 (812) 552-98-09
Email: rakcheeva_lp@spbstu.ru
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