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Supported design types
up to 30 bar
Maximum reaction temperature
up to 200 °C
up to 50 ml/min
Maximum reagent volumetric flow rate
Equipment
Miprowa microreactor system
Equipment
ART PL37 microreactor system
Equipment
Lonza FlowPlate microreactor system
Minimum reagent consumption
up to 0.1 ml/min
The Chemical Laboratory of the Saint Petersburg Technopark offers microreactor synthesis of organic compounds — a modern method that allows for precise control of chemical reaction parameters, increased yield of the target product, and minimized reagent consumption.
The technology is based on the continuous supply of components into a small-volume reaction cell with precise regulation of temperature, pressure, and contact time. This is particularly effective for thermosensitive, multicomponent, and fast-acting reactions.
Unlike classic batch synthesis, where key factors are concentration, stirring, process temperature, and reaction time, in continuous flow synthesis, these are primarily residence time, pressure, process temperature, and stirring.
The technology is based on the continuous supply of components into a small-volume reaction cell with precise regulation of temperature, pressure, and contact time. This is particularly effective for thermosensitive, multicomponent, and fast-acting reactions.
Unlike classic batch synthesis, where key factors are concentration, stirring, process temperature, and reaction time, in continuous flow synthesis, these are primarily residence time, pressure, process temperature, and stirring.
Key advantages of microreactor synthesis:
The choice of a microreactor system depends on the type of task. The Saint Petersburg Technopark features more than 3 microreactor systems with various channel geometries.
- efficient mass transfer due to mixing of reaction components in a laminar flow via diffusion (whereas in batch synthesis, mixing occurs in a turbulent mode),
- efficient heat transfer due to a higher surface area to volume ratio of the microreactor (this value is lower for a classic reactor),
- ability to safely conduct fast and highly exothermic reactions, thanks to rapid heat removal from the reaction mass,
- technical capability to implement stages requiring different temperature regimes, thanks to rapid controlled heating,
- technical capability to work under pressure, which means: implementation of reactions in liquid-gas systems and processes requiring supercritical conditions.
The choice of a microreactor system depends on the type of task. The Saint Petersburg Technopark features more than 3 microreactor systems with various channel geometries.
Applications
Pharmaceutical products
Petrochemical products
Production of intermediate synthesis products
Development of efficient organic compound synthesis technology
Laboratory research and R&D
Optimization of multi-stage production methods
Work stages
Assessment of objectives, reagents, and potential substance and parameter constraints.
Selection of optimal temperature regimes, flows, pressure, and contact time.
Reaction is conducted with high dosing precision and parameter control.
Intermediate and final quality control of synthesis products (conversion rate control and quantification primarily by HPLC and NMR methods)
The customer is provided with protocols, recommendations for scaling, and methodology improvement.
Advantages
Increased safety when working with aggressive reagents
Rapid scalability
High precision parameter control
Minimal volumes and low waste levels
Cost
Service name
Cost
For St. Petersburg SMEs (-20%)
For St. Petersburg UAS R&D Center residents (-30%)
Laboratory microreactor synthesis on LLs-LigandenLaborSynthese. Model reaction for isopropyl acetate synthesis
Single-stage laboratory microreactor synthesis on LLs-LigandenLaborSynthese (1 hour)
Single-stage laboratory microreactor synthesis on LLs with automated sampling (1 hour) with report
13,700 ₽
18,400 ₽
31,800 ₽
10,960 ₽
14,720 ₽
25,440 ₽
9,590 ₽
12,880 ₽
22,260 ₽
Pilot single-stage microreactor synthesis (1 hour), with report preparation
13,700 ₽
10,960 ₽
9,590 ₽
Pilot single-stage microreactor synthesis (1 hour)
13,600 ₽
10,880 ₽
9,520 ₽
Laboratory single-stage microreactor synthesis on PolyMatSphere-Ls (1 hour), with report preparation
13,800 ₽
11,040 ₽
9,660 ₽
Laboratory single-stage microreactor synthesis on PolyMatSphere-Ls (1 hour)
12,500 ₽
10,000 ₽
8,750 ₽
Laboratory microreactor synthesis on MRT Ultra-HPR&D. Model reaction of isopropyl acetate synthesis
13,700 ₽
10,960 ₽
9,590 ₽
Laboratory microreactor synthesis on MRT Ultra-HPR&D. Model reaction of fructose dehydration.
13,600 ₽
10,880 ₽
9,520 ₽
Laboratory microreactor synthesis on MRT Ultra-HPR&D in 1 stage, using hydrogen (1 hour), with report preparation
7,600 ₽
6,080 ₽
5,320 ₽
Laboratory microreactor synthesis on MRT Ultra-HPR&D in 1 stage (1 hour), with report preparation
7,600 ₽
6,080 ₽
5,320 ₽
Laboratory microreactor synthesis in 1 stage on MRT Ultra-HPR&D (1 hour)
6,300 ₽
5,040 ₽
4,410 ₽
Recording of a 1H NMR spectrum with sample preparation and extended report generation
33,800 ₽
27,040 ₽
23,660 ₽
Laboratory microreactor synthesis on LLs-LigandenLaborSynthese in 1 stage (1 hour) with report preparation
22,400 ₽
17,920 ₽
15,680 ₽
Order service
Contacts
Boris Nikolaev
Chief Researcher of the Chemical Laboratory of the Saint Petersburg Technopark
+7 (812) 670-10-85 (ext. 132)
Address
30 Zanevsky Ave, Bldg 2
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