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Determination of residual moisture by the Karl Fischer method

High-precision determination of water content in substances using the Karl Fischer method. Suitable for pharmaceuticals, chemical synthesis, and product quality control.
Equipment
METROHM 915 KF TI-TOUCH Volumetric Titrator
Moisture determination range
from 0.01 to 100%
Minimum detectable amount of water
up to 10 mg H₂O
up to 1%
Measurement error
Average analysis time per sample
5–15 min
The Chemical Laboratory of the Saint Petersburg Technopark provides residual moisture determination services using the Karl Fischer method. The method is based on precise quantitative measurement of water content in solid, liquid and semi-solid substances by titration involving iodine.

Analysis is performed on a modern volumetric titrator, ensuring high precision, reproducibility and sensitivity with minimal sample volumes. The method is suitable for assessing residual moisture in pharmaceutical substances, reagents, powders, lyophilized preparations and solutions.

Results can be used for quality control, stability confirmation and compliance with regulatory documentation.
Applications
Residual moisture control in pharmaceutical substances
Analysis of lyophilization and drying products
Testing of chemical reagents and solvents
Assessment of material stability and storage
Work stages
Sample receipt and registration, weighing, selection of suitable solvent and analysis conditions.
Advantages
High precision with small sample weights
Method versatility — for liquid and solid substances
Rapid analysis in laboratory conditions
Cost
Service name
Cost
For St. Petersburg SMEs (-20%)
For St. Petersburg UAS R&D Center residents (-30%)
Determination of water (residual moisture) by the Karl Fischer method
Determination of water (residual moisture) by the Karl Fischer method, with report preparation
1,800 ₽
3,200 ₽
1,440 ₽
2,560 ₽
1,260 ₽
2,240 ₽

Order service

Contacts

Boris Nikolaev
Chief Researcher of the Chemical Laboratory of the Saint Petersburg Technopark
+7 (812) 670-10-85 (ext. 132)
Address
30 Zanevsky Ave, Bldg 2
Map
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