Determination of residual moisture by the Karl Fischer method
Determination of residual moisture by the Karl Fischer method
High-precision determination of water content in substances using the Karl Fischer method. Suitable for pharmaceuticals, chemical synthesis, and product quality control.
The Chemical Laboratory of the Saint Petersburg Technopark provides residual moisture determination services using the Karl Fischer method. The method is based on precise quantitative measurement of water content in solid, liquid and semi-solid substances by titration involving iodine.
Analysis is performed on a modern volumetric titrator, ensuring high precision, reproducibility and sensitivity with minimal sample volumes. The method is suitable for assessing residual moisture in pharmaceutical substances, reagents, powders, lyophilized preparations and solutions.
Results can be used for quality control, stability confirmation and compliance with regulatory documentation.
Applications
Residual moisture control in pharmaceutical substances
Analysis of lyophilization and drying products
Testing of chemical reagents and solvents
Assessment of material stability and storage
Work stages
Sample receipt and registration, weighing, selection of suitable solvent and analysis conditions.
Moisture determination by Karl Fischer volumetric titration. Monitoring of the titration process.
Issuance of numerical data indicating water content (in % or mg) as printouts; a brief report if necessary.
Advantages
High precision with small sample weights
Method versatility — for liquid and solid substances
Rapid analysis in laboratory conditions
Cost
Service name
Cost
For St. Petersburg SMEs (-20%)
For St. Petersburg UAS R&D Center residents (-30%)
Determination of water (residual moisture) by the Karl Fischer method
Determination of water (residual moisture) by the Karl Fischer method, with report preparation
1,800 ₽
3,200 ₽
1,440 ₽
2,560 ₽
1,260 ₽
2,240 ₽
Order service
Contacts
Boris Nikolaev
Chief Researcher of the Chemical Laboratory of the Saint Petersburg Technopark